Table 3. Cytotoxicity Results of the Synthesized Probes.
| IC50 (μM) |
||
|---|---|---|
| compd | HEK293A-α1A-AR | HEK293A-α1D-AR |
| doxazosin | 19 ± 2 | 22 ± 2 |
| 1a | >100 | >100 |
| 1b | >100 | 85 ± 2 |
| 1c | 12 ± 0.2 | 32 ± 2 |
| 1d | >100 | >100 |
| 1e | 26 ± 3 | 17 ± 0.2 |
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