Table 1. MCT1 IC₅₀ Values of N,N-Dialkyl/Aryl Cyanocinnamic Acids.

Sl. No.	X	% yielda	MCT1 IC50 (μM)b
10	N,N-dimethyl	72	0.14 ± 0.05
11	N,N-diethyl	75	0.07 ± 0.02
12	N,N-dipropyl	67	0.01 ± 0.01
13	N,N-dibutyl	65	0.03 ± 0.00
14	N,N-diisobutyl	61	0.10 ± 0.05
15	N,N-dipentyl	70	0.14 ± 0.02
16	N,N-dihexyl	68	0.88 ± 0.18
17	N,N-diallyl	60	0.11 ± 0.03
18	N,N-dipropargyl	62	0.40 ± 0.02
19	N,N-diphenyl	76	0.03 ± 0.00
20	pyrrolidinyl	62	0.07 ± 0.01
21	piperidinyl	67	0.14 ± 0.03

^aStarting from aldehydes.

^bAverage IC₅₀ values of minimum three separate experiments. Values reported as avg ± SEM.