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Binding model comparison of designed compounds with PF-04217903. (A) Binding pose of compound 15g (purple) and PF-04217903 (green) with c-Met. (B) Overlay of 15a (blue), 15c (pink), 15e (orange), and 15g (purple) in the same cavity along with PF-04217903 (green) as the reference molecule.
