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| IC50 (nM)a | 22e | JNJ38877605 | Crizotinib |
|---|---|---|---|
| EBC-1 | 45.0 ± 12.7 | 9.5 ± 2.0 | 21.8 ± 6.5 |
| MKN-45 | 90.9 ± 17.4 | 10.9 ± 0.4 | 38.1 ± 8.8 |
| SNU-5 | 70.2 ± 19.6 | 15.8 ± 3.2 | 20.4 ± 14.4 |
| BaF3/TPR-Met | 203.2 ± 4.4 | 17.6 ± 2.2 | 127.4 ± 8.1 |
The IC50 values are shown as the mean ± SD (nM) from three separate experiments.
