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Daily wheel-running activity under a standard 12hL:12hD cycle. (A) Actimetry sample from a single animal, double-plotted and centered at ZT0 (7h00) for a total period of 11 days under standard baseline conditions. (B) Differences for total wheel counts under actimetry recording during the light versus dark period. Analysis was done using Student t test and found to be highly significant. Asterisks represents Student t test significance (P < 0.00001).
