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EC50 and fold change for DT310, DT320, and doxorubicin on parental 4T1 or 4T1 stem cells
| Treatment | Parental EC50 4T1 cell line grown on plastic surface | EC50 4T1 stem cells in suspension culture | Fold change |
|---|---|---|---|
| DT310 | 14.4 μM | 141 μM | 9.8 |
| DT320 | 19.7 μM | 50 μM | 2.5 |
| doxorubicin | 4.7 μM | 630 μM | 134.0 |
For control, the EC50 of an inactive analog of DT310 and DT320, Orange #1, was also determined (EC50 = 398 μM) on 4T1 stem cells
