Skip to main content
. Author manuscript; available in PMC: 2015 May 18.
Published in final edited form as: J Biomol Screen. 2011 Feb;16(2):183–191. doi: 10.1177/1087057110389040

Figure 5. Scatter plot analysis results from the HTS LOPAC screen.

Figure 5

All data from 12 assay plates including controls is displayed. The nominal cutoff for activators of this assay is shown by the dashed line. The positive control is shown as red circles, compounds in black and low control in green. Active compounds were identified based on their average result being greater than the nominal cutoff threshold value of 19.61%. In this display, more than 30 test wells have activity exceeding the threshold value which reflects the reproducibility of the compounds being tested in triplicate. Note this assays identifies negative modulators of RORα and PGC-1α interaction which are displayed as negative % activation.