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Effect of UDCA on histological extent of CDCA-induced liver injury in hamsters
|
Grade |
||||
| Findings | - | ± | + | |
| Normal | Vacuolation (Hydropic swelling) | 9 | 0 | 0 |
| Control | 0 | 2 | 7 | |
| UDCA 150 mg/kg | 9 | 0 | 0 | |
| Normal | 8 | 1 | 0 | |
| Control | Cell infiltration | 8 | 1 | 0 |
| UDCA 150 mg/kg | 7 | 2 | 0 | |
| Normal | 8 | 1 | 0 | |
| Control | Focal necrosis | 8 | 1 | 0 |
| UDCA 150 mg/kg | 7 | 2 | 0 | |
UDCA: Ursodeoxycholic acid; CDCA: Chenodeoxycholic acid. Grades are as follows: -: no change, ±: slight change, +: mild change.
