Table 7.
Severe acute pancreatitis-antibiotic prophylaxis is inefficient in severe acute pancreatitis; results of two randomized controlled double-blind multicentric trials
|
Isenmann[79] |
Dellinger[80] |
|||
| 2004 | P value | 2005 | P value | |
| Patients (n) | 114 | 100 | ||
| Treatment (n)1 | 48 | 40 | ||
| Placebo (n) | 41 | 40 | ||
| Infection of necrosis | ||||
| Treatment | 12%1 | NS | 23%2 | NS |
| Placebo | 14%1 | 15%2 | ||
| Need for surgery | ||||
| Treatment | 17%1 | NS | 23%2 | NS |
| Placebo | 11%1 | 24%2 | ||
| Hospital mortality | ||||
| Treatment | 12%1 | NS | 20%2 | NS |
| Placebo | 9%1 | 18%2 | ||
1
Statistical comparison of treatment and placebo group data 2004;
2
Data 2005.