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Increased S6K1 activity increases neuronal complexity in cultured cells. (A and B) Representative images of an eGFP-expressing rat primary cortical neuron 2 wk after infection with (A) control virus and (B) S6K1CA virus. Concentric circles with 100- and 200-μm diameter were drawn around the cell soma for Sholl analysis. (C) S6K1CA expression increases neuronal complexity in primary cortical neurons (F1,15 = 9.5, *P < 0.05; n = 7–10). Error bars represent mean ± SEM.
