Fig. 5.

Both mHsp60 rings are in the post ATP-hydrolysis state. A side view of the 14 ADP molecules as they are positioned in the structure is shown. Nucleotides are shown as sticks and are labeled according to their subunits. In addition, a F_o-F_c omit electron density map of the 14 nucleotides is shown. The map was calculated by omitting the nucleotides and magnesium atoms from the final model and performing five cycles of refinement using REFMAC [version 5.7.32 (58)]. The map was contoured at a 3σ cutoff.