Table 3.

Adjudicated hospitalization events in the PACE study

Event			Adjudicated based on following clinical criteria
Cardiovascular disease (CVD)
Myocardial infarction	Clinical symptoms		Jaw pain or chest Pain
	ECG markers		Major Q wave
			ST elevation with or without Q wave
	Cardiac biomarkers		Troponin I
			CK-MB or CK total
Congestive heart failure/Volume overload	Clinical symptoms		Dyspnea on exertion or rest
			Pulmonary edema or pulmonary congestion
	Radiographic evidence		Inspiratory crackles
			S3 gallop
	Physical exam		Jugular venous distension
			Peripheral edema
Procedures	Atherosclerotic CVD (ASCVD)		Percutaneous transluminal coronary angioplasty (PTCA)
			Coronary artery bypass graft (CABG)
			Carotid endarterectomy
			Abdominal aortic aneurysm repair
	Peripheral vascular disease (PVD)		Peripheral angioplasty
			Peripheral bypass
			Limb amputation
Cerebrovascular Accident (CVA) clinical and supportive CT and MRI evidence	Large artery stenosis		>50% stenosis of major artery
			Cerebral cortical impairment
			Brainstem/cerebellar dysfunction
	Cardioembolism
	Small-artery occlusion (lacunar)		Clinical lacunar syndromes
			No evidence of cortical dysfunction
	Other etiology		Nonatherosclerotic vasculopathies
			Hypercoagulable states or hematologic disorders
	Undetermined etiology
Systemic infections	Sepsis	Central Nervous system	Access -related
	Respiratory/GI tract	Fungal	Skin
	Peritonitis	Septic Arthritis	Osteomyelitis
Fractures	All		Traumatic
	Hip/ Vertebral compression		Traumatic