Table 1. Patient Characteristics.
ID | Age | Gender | Clinical TNM Stage | Induction C/T | Concurrent C/T | Pathologic Response | Pre-TMT FAM84B IHC Intensity | Post-TMT FAM84B IHC Intensity |
---|---|---|---|---|---|---|---|---|
Microarray & RT-PCR | ||||||||
316 | 48 | M | T3N1M1b | None | DP | CR | 2+ | NA |
833 | 62 | M | T2N1M0 | None | TP | CR | 2+ | NA |
743 | 42 | M | T3N1M1a | None | TP | nCR | NA | NE |
040 | 52 | M | T3N1M0 | None | DP | nCR | NA | 2+ |
843 | 45 | M | T3N1M1b | TP-HDFL | TP | nCR | 3+ | 3+ |
146 | 63 | M | T3N0M1a | TP-HDFL | TP | CR | 2+ | NA |
690 | 55 | M | T3N1M0 | None | DP | CR | 2~3+ | NA |
817 | 48 | M | T1N1M1a | TP-HDFL | TP | CR | 2~3+ | NA |
153 | 47 | M | T3N1M0 | TP-HDFL | TP | CR | NA | NA |
694 | 54 | M | T3N1M0 | None | PF | nCR | 2+ | 3+ |
995 | 53 | M | T3N1M0 | TP-HDFL | TP | CR | 1+ | NA |
450 | 49 | M | T3N1M1a | TP-HDFL | TP | nCR | 3+ | 2~3+ |
970 | 45 | M | T3N1M0 | None | TP | CR | 0 | NA |
554 | 64 | M | T3N1M0 | TP-HDFL | TP | CR | NA | NA |
809 | 52 | M | T3N1M1a | None | PF | nCR | 2+ | 2+ |
490 | 65 | M | T4N1M1b | None | PF | nCR | 3+ | 3+ |
618 | 56 | M | T3N1M0 | TP-HDFL | TP | nCR | 1~2+ | 3+ |
193 | 51 | M | T3N1M0 | None | TP | CR | 2~3+ | NA |
967 | 62 | M | T3N1M0 | TP-HDFL | TP | nCR | 2+ | 2+ |
825 | 70 | M | T3N1M0 | TP-HDFL | TP | nCR | 2~3+ | 2+ |
210 | 64 | M | T3N1M0 | None | PF | nCR | 2+ | 2+ |
RT-PCR only | ||||||||
067 | 50 | M | T3N1M1b | TP-HDFL | PF | nCR | 2+ | 2+ |
906 | 74 | M | T3N1M0 | None | TP | CR | NA | NA |
609 | 50 | M | T3N1M0 | TP-HDFL | TP | nCR | 2+ | NE |
887 | 48 | M | T3N1M0 | None | DP | nCR | 2+ | 3+ |
951 | 55 | F | T3N1M0 | None | TP | nCR | 2+ | 1~2+ |
486 | 50 | M | T3N0M0 | TP-HDFL | TP | CR | 3+ | NA |
557 | 70 | M | T3N1M0 | None | TP | nCR | 3+ | 2~3+ |
085 | 37 | M | T3N1M0 | None | DP | nCR | 2~3+ | NE |
834 | 50 | M | T3N1M0 | None | CTP | nCR | 0~1+ | 2+ |
181 | 49 | M | T3N1M0 | None | CTP | CR | 2+ | NA |
890 | 63 | M | T3N1M0 | None | CTP | CR | 2+ | NA |
532 | 37 | M | T3N0M0 | None | CTP | nCR | 2~3+ | NE |
141 | 64 | M | T3N1M0 | None | TP | CR | 1~2+ | NA |
847 | 40 | M | T3N1M0 | None | CTP | nCR | 1+ | 2+ |
632 | 47 | M | T3N1M0 | None | CTP | CR | 0 | NA |
565 | 47 | M | T3N1M0 | None | CTP | nCR | 1+ | 2+ |
Abbreviations: C/T, chemotherapy; TMT, tri-modality therapy, IHC, immunohistochemistry; M, male; F, female; CR, complete response; nCR, non-complete response; NA, not available; NE: not evaluable.
Chemotherapy regimens: TP-HDFL, paclitaxel (80 mg/m2) on days 1 and 8, cisplatin (35 mg/m2) on days 2 and 9, fluorouracil (2000 mg/m2) and leucovorin (300 mg/m2) on days 2 and 9; PF, cisplatin (30 mg/m2) and fluorouracil (425 mg/m2) once weekly; TP, paclitaxel (35 mg/m2) on days 1 and 4 of each week and cisplatin (15 mg/m2) on days 2 and 5 of each week; DP, docetaxel (20 mg/m2) and cisplatin (20 mg/m2) once weekly; CTP, cetuximab (400 mg/m2) on week -1 and (250 mg/m2) once weekly, paclitaxel (35 mg/m2) on days 1 and 4 of each week and cisplatin (15 mg/m2) on days 2 and 5 of each week.