FIG. 5.

Contractile responses in mesenteric arterial rings of control and T-exposed pregnant rats. Endothelium-denuded mesenteric arterial rings were incubated in Krebs buffer, and then vascular contractile responses were taken to cumulative additions of KCl (A), phenylephrine (B), and Ang II (C). Contractions to Ang II were also taken in the presence of losartan (10 μM). K⁺ depolarizing contractions are presented as absolute tension (mN/mm) and as the percentage of maximal KCl contractions. Phenylephrine and angiotensin II contractions are presented as percentages of their maximal contractions, as well as percentages of 80 mM KCl contractions. Values are means ± SEM. Mesenteric arterial rings (n = 10 to 12) from 8 rats of each group were used.