FIG. 1.

Effect of obesity on follicle number. At 6, 12, 18, or 24 wk of age, mice were euthanized and ovaries collected. One ovary was fixed in 4% paraformaldehyde, complete serial sections were mounted, and healthy follicles were classified and counted in both lean and obese mice (A–D); healthy primordial follicle number (A); healthy primary follicle number (B); healthy secondary follicle number (C); and healthy antral follicle number (D). Bars represent means ± SEM. *Significant (P < 0.05; † = P < 0.1; n = 4) differences from respective lean group.