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Changes in the pharmacokinetic parameters of voriconazole after a single intravenous administration at 200 mg by CYP2C19 genotypes.
Notes: (A) Cmax, maximum plasma concentration; (B) AUClast, area under the concentration–time curve (AUC) from dosing to the last quantifiable concentration; (C) AUCinf, AUC from dosing to infinity.
Abbreviations: hr, hours; EM, extensive metabolizer; IM, intermediate metabolizer; PM, poor metabolizer.
