Table 3.
Effects of the aqueous extract from Cissus sicyoides (AECS) on biochemical parameters in the blood from alloxan-induced diabetic rats
Parameter | Group | ||
Control | AECS 100 mg/kg | AECS 200 mg/kg | |
Glucose (mg/dL) | |||
Before | 264.8 ± 12.66 | 252.2 ± 8.44 | 250.8 ± 10.74 |
After | 248.1 ± 11.65 | 218.1 ± 16. 21 | 188.0 ± 16.22* |
Cholesterol (mg/dL) | |||
Before | 58.4 ± 3.92 | 56.6 ± 3.19 | 63.0 ± 2.55 |
After | 55.4 ± 2.91 | 50.1 ± 5.89 | 54.6 ± 2.29 |
Triglycerides (mg/dL) | |||
Before | 169.8 ± 8.61 | 256.4 ± 24.60 | 165.4 ± 12.87 |
After | 124.1 ± 8.02 * | 132.5 ± 9.02 * | 86.4 ± 7.56 * |
ALT (IU/l) | |||
Before | 20.0 ± 1.33 | 28.6 ± 2.15 | 20.8 ± 1.62 |
After | 34.7 ± 2.89 * | 41.2 ± 2.71 * | 29.8 ± 2.22 |
AST (IU/l) | |||
Before | 60.5 ± 3.90 | 62.2 ± 5.52 | 75.9 ± 4.74 |
After | 85.5 ± 4.35 * | 89.3 ± 7.03 * | 88.3 ± 3.73 |
Values are means ± SEM of 8 to 18 animals per group. The blood was collected from the orbital sinus, 48 h after the alloxan administration, 60 mg/kg, i.v., before and 1 h after the last administration of distilled water (controls) or AECS, daily for 4 days. *p < 0.05 as compared to the same group, 48 h after the alloxan injection (ANOVA and Tukey as the post hoc test).