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. 2015 Mar 31;6(1):84–94. doi: 10.1002/jcsm.12008

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© 2015 The Authors. Journal of Cachexia, Sarcopenia and Muscle published by John Wiley & Sons Ltd on behalf of the Society of Cachexia, Sarcopenia and Wasting Disorders

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Serotonin signalling in C26 and Lewis lung carcinoma tumour-bearing mice. (A) Schematic view of genes involved in serotonin signalling. (B) Heat map of fold changes of expressions of genes involved in serotonin signalling. (C) Serotonin level in brain relative to control mice in C26 and Lewis lung carcinoma tumour-bearing mice. Values are expressed as mean ± SEM. C, sham-injected control; tumour bearing, injected with 1 × 106 tumour cells; DNTP, 7,8-dihydroneopterin triphosphate; 6PTS, 6-pyruvoyl-tetrahydropterin; q-dbt, q-dihydrobiopterin; TRP, tryptophan; 5HT, 5-hydroxytryptamine (serotonin); MAO, monoamine oxidase; and ALDH, aldehyde dehydrogenase.