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. 2004 Jul 1;18(13):1618–1629. doi: 10.1101/gad.1200804

Figure 5.

Figure 5.

Loops containing G4 DNA form in plasmids transcribed in E. coli. (A) Examples of loops formed in pPH600 (Sγ3) transcribed in E. coli strain NM 256 [AB1157 (λDE3) rnh::cat recQ::kan]. Bar, 200 nm. (B) Examples of GQN1 cleavage of loops formed in pPH600 (Sγ3) transcribed in E. coli NM 256. Arrows indicate broken loops. Bar, 200 nm. (C) Sensitivity of loops formed in E. coli to GQN1 cleavage. Loops were analyzed by EM and were scored as cleaved if they were opened and contained clearly visible DNA ends. (n) Number of molecules scored.