FIG. 1.

Messenger RNA expression profiles of the MT-MMPs during the rat periovulatory period. The mRNA expression profiles of the MT-MMPs Mmp14 (A), Mmp16 (B), Mmp25 (C), Mmp15 (D), and Mmp17 (E) in the intact ovary, granulosa cells, and residual ovarian tissue collected from eCG-primed immature rats at 0 h (48 h after eCG) or at 4, 8, 12, and 24 h after administration of hCG are shown. Relative levels of mRNA were normalized to L32 in each sample and expressed as the fold-change relative to 0 h. Data are presented as the mean ± SEM (n = 3–4 per time point) of the fold-change in mRNA levels, and different superscripts indicate significant changes (P < 0.05) in mRNA levels within an MT-MMP panel.