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. 2014 Jul 29;22(9):1580–1592. doi: 10.1038/mt.2014.112

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Copyright © 2014 American Society of Gene & Cell Therapy

This work is licensed under a Creative Commons Attribution 3.0 Unported License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/3.0/

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Effect of pig CSF1-Fc on male reproductive tract. Mice were injected with PBS or 1 µg/g pig CSF1-Fc for four days prior to sacrifice on day 5. Serum was collected as well as tissue, which was fixed and processed as described in materials and methods. Graphs show the mean ± SEM. Significance is indicated by *P < 0.05 using unpaired t-tests. (a) Representative sections show macrophages within the testicular interstitium, stained with a macrophage marker, Mac2. Bar = 50µM. (b) Serum levels of testosterone and (c) Luteinizing hormone.