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. Author manuscript; available in PMC: 2015 May 18.
Published in final edited form as: Fertil Steril. 2014 Jun 2;102(1):10–18. doi: 10.1016/j.fertnstert.2014.05.019

FIGURE 1.

FIGURE 1

Effect of the peri-implantation environment on mouse placentation and fetal growth. (A) Fetal and placental weights of embryos at embryonic day 19 resulting from the transfer of naturally conceived blastocysts to control and superovulated recipient mice. Fetal and placental weights were significantly smaller in the superovulated group. Data are expressed as mean ± SEM. (B) Placental histology differed significantly in the offspring of control compared with superovulated recipients. Placentas from superovulated recipients showed attenuated branching with limited invasion of the junctional zone by the labyrinth zone with a decrease in the junctional:labyrinth zone ratio. aP<.05 vs. natural mating. bP<.001 vs. natural mating. Adapted from Mainigi et al. (63).