TABLE IV.

Repeated Measures Models for Predictors of BMI z-Score During and After Treatment in Pediatric ALL Survivors

	From diagnosis to end of treatment			From end of treatment to 5 years post-treatment
	β	95% CIa	P	β	95% CIb	P
Male gender	0.17	−0.11, 0.46	0.22	0.21	−0.09, 0.52	0.17
Receiving CRT	0.16	−0.24, 0.56	0.43	−0.42	−0.94, 0.10	0.11
Age at diagnosis	−0.01	−0.04, 0.03	0.67	−0.004	−0.04, 0.03	0.82
High risk ALL	−0.37	−0.69, −0.06	0.02	−0.002	−0.36, 0.35	0.99
Months since diagnosis	−0.004	−0.01, 0.005	0.38	0.001	−0.003, 0.005	0.56
BMI z-score at diagnosis	0.46	0.34, 0.59	<0.0001	0.91	0.69, 1.12	<0.001
Overweight/obese at diagnosis	1.02	0.64, 1.41	<0.0001	0.80	0.10, 1.50	0.03
Change in BMI z-score during treatment		—		0.82	0.59, 1.04	<0.001

^aAdjusted for gender, receiving CRT, age at diagnosis (continuous), treatment risk category (high vs. standard risk ALL), months since diagnosis (continuous), and BMI z-score at diagnosis (continuous). Weight status at diagnosis (overweight/obese vs. healthy weight/underweight) was evaluated in separate models with all predictors except for BMI z-score to avoid collinearity;

^bβ and 95%CI were additionally adjusted for change in BMI z-score during treatment (continuous).