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Plasma ADMA concentrations (A) and L-arginine/ADMA ratio (B) at baseline and at 8 weeks. The subjects received 800 mg/day of L-citrulline orally for 8 weeks. Following overnight fasting, blood samples were drawn to analyze plasma ADMA and L-arginine concentrations before and after L-citrulline supplementation. Values are expressed as mean with their standard errors. ADMA, asymmetric dimethylarginine. Significant difference from baseline score, **p < 0.01. n = 22.
