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. Author manuscript; available in PMC: 2015 May 18.
Published in final edited form as: Dev Biol. 2011 Jul 1;357(1):152–164. doi: 10.1016/j.ydbio.2011.06.041

Figure 2. Adamts5 null mice have enlarged and malformed pulmonary valves.

Figure 2

H & E stained frontal sections of the PV from WT (A, E) and Adamts5−/− (B, F) hearts at E14.5 (A, B) and E17.5 (E, F) same magnification are shown. Three-dimensional reconstructions of WT (C, G) and Adamts5−/− mice (D, H) were generated from histological sections of E14.5 and E17.5 PV. Lt- left cusp of the PV (blue); Rt- right cusp of the PV (white); An-anterior cusp of the PV (green); D-dorsal; V-ventral; Scale bars: A = 50 μm; C=75 μm; E =150 μm; G = 200 μm. Corresponding quantitative data from reconstructions are listed in Supplemental Table I.