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. 2015 May 13;15:41. doi: 10.1186/s12905-015-0199-9

Table 1.

Comparison between patients with and without vertebral fractures (n = 207)

Group 0: Women without vertebral fractures (n = 73) mean (SD) Group 1: Women with grade 1 vertebral fractures (n = 96) mean (SD) Group 2: Women with grade 2 or 3 vertebral fractures (n = 38) mean (SD) P value P value 0 vs. 2/3 P value 0 vs. 1 P value 1 vs. 2/3
Age (years) 57,57 (5,92) 60,01 (8,12) 63,64 (8,59) <0.001 <0.001 0,11 0,04
Body mass index (kg/m2) 31,15 (15,54) 31,38 (12,85) 30,25 (5,43) 0,8996 1,00 1,00 1,00
Number of parity 4,78 (1,8) 4,71 (2,5) 5,24 (2,6) 0,49 0,99 1,00 0,72
Years since menopause 7,60 (6,93) 9,40 (8,64) 14,86 (10,83) <0.001 <0.001 0,55 0,004
SHBG (ng/ml) 52,46 (27,11) 57,87 (28,33) 58,26 (29,75) 0,4044 0,91 0,65 1,00
β-CTX (ng/ml) 0,43 (0,24) 0,43 (0,24) 0,41 (0,24) 0,9159 1,00 1,00 1,00
PTHi (pg/ml) 41,14 (36,83) 39,21 (31,46) 35,89 (5,82) 0,7166 1,00 1,00 1,00
E2 (pmol/l) 47,49 (43,83) 43,42 (51,07) 41,80 (21,70) 0,7689 1,00 1,00 1,00
FEI (pmol/nmol) 12,11 (11,50) 10,64 (18,29) 9,28 (5,94) 0,6026 0,99 1,00 1,00
S-DHEA (μmol/l) 2,34 (1,24) 1,97 (0,98) 2,08 (1,35) 0,1138 0,78 0,12 1,00
25 (OH)D3 (ng/ml) 13,20 (9,54) 12,21 (8,07) 24,42 (3,96) 0,1495 0,41 1,00 0,16
Osteocalcin (μg/l) 24,21 (13,95) 23,83 (12,83) 23,61 (14,33) 0,9722 1,00 1,00 1,00
Lumbar spine BMD (g/cm2) 0,97 (0,26) 0,98 (0,18) 1,02 (0,15) 0,4367 0,62 1,00 0,91
Lumbar spine T-score -1,29 (1,20) -1,40 (1,55) -1,09 (1,25) 0,5088 1,00 1,00 0,74
Total hip BMD (g/cm2) 0,93 (0,13) 0,93 (0,14) 0,86 (0,42) 0,2162 0,31 1,00 0,34
Total hip BMD T-score -0,79 (1,11) -0,78 (1,20) -0,71 (1,01) 0,9411 1,00 1,00 1,00

Mean ± SD : m (SD) *: <0.05 **: < 0.001. One way analysis of variance+Post hoc test (Bonferroni) BMD bone mineral density, BMI body mass index, E estradiol, FEI free estrogen index, PTH parathormone (PTH) intact; S-DHEA dehydroepiandrosterone sulphate, SHBG sex hormones binding globulin, T testosterone