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. Author manuscript; available in PMC: 2015 May 18.
Published in final edited form as: Neurosci Lett. 2009 Apr 23;458(3):111–115. doi: 10.1016/j.neulet.2009.04.039

Fig. 2.

Fig. 2

Particulate β-glucan inhibits TLR4-mediated cytokine production by microglia. Primary microglia were left untreated (control) or were stimulated with β-glucan (100 µg/ml), LPS (1 µg/ml) or combination of β-glucan and LPS for 16 h (Co-Tx). A subset of cells was pre-treated with β-glucan (Pre-Tx) for 2 h (A) or 24 h (B) before stimulation with LPS for 16 h in continuous presence of β-glucan. Supernatants were then collected, and levels of TNF-α and IL-6 were measured using ELISA. Data are presented as mean ± SEM, n = 3. *p < 0.05 compared with control. **p < 0.05 compared with LPS alone.