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. 2015 Apr 7;2(5):445–455. doi: 10.1002/acn3.181

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© 2015 The Authors. Annals of Clinical and Translational Neurology published by Wiley Periodicals, Inc on behalf of American Neurological Association.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Differences in proportions and absolute numbers of adaptive immune cells: CD4+ and CD8+ T cells and their subsets (HLA-DR+ effector cells and CD56+ cytotoxic cells), CD19+ B cells, TCRγ/δ T cells, TCRγ/δ CD4+ T cells, TCRγ/δ CD8+ T cells, and TCRγ/δ double negative T cells. The two left panels in each row represent proportions and absolute numbers of specific cell populations in the blood, while the two right panels represent proportions and absolute numbers of the same cell populations in the cerebrospinal fluid. Each diagnostic category corresponds to one vertical box-and-whisker plot. The boxes show the median and 25–75% range, while the whiskers indicate minimum and maximum values for each diagnostic category. The scatter dot plots represent data from individual patients. *P < 0.05, **0.001 < P < 0.05, ***P < 0.001.