Figure 3.

Weighted connection strength overlaid on an inflated cortical surface for the (A) left, and (B) right hemispheres. Only connection strengths greater than the median are displayed. Of note is the bright occipital/parietal region in controls that is not seen in childhood absence epilepsy (CAE). This implies that the cortical thickness of the occipital lobe in controls is most highly correlated with the rest of the brain, whereas this is not the case in the CAE group. Also evident is a large increase in the anterior cingulate cortex in the disease group. These changes are apparently part of an overall trend for posterior dominance in controls and anterior dominance in CAE. The activation pattern is broadly similar in both left and right hemispheres, with increased medial and lateral frontal and decreased posterior connectivity in the CAE group.