Table 6. Reconstruction of 9-gene BIOGRID network related to Human HeLa cell cycle.
| Network | PPV | Recall | F score |
|---|---|---|---|
| BioGrid network in Sambo et al. 2008 | |||
| C-NET (Sambo et al. 2008) | 0.36 | 0.44 | 0.40 |
| Broken stick method | 0.36 | 0.44 | 0.40 |
| Bartlett's method | 0.50 | 0.44 | 0.47 |
| TSNI Integral | 0.10 | 0.44 | 0.17 |
| BioGrid network in Lozano et al. 2009 | |||
| GGGM (Lozano et al. 2009) | 0.50 | 0.72 | 0.59 |
| Broken stick method | 0.63 | 0.50 | 0.56 |
| Bartlett's method | 0.65 | 0.55 | 0.60 |
| TSNI Integral | 0.22 | 0.30 | 0.26 |
Recovery of 9-gene BIOGRID network involved in human HeLa cell cycle by applying broken stick and Bartlett’s feature selection methods compared to TSNI integral. These two versions of BIOGRID network were used to assess proposed methods in Sambo et al. 2008 and Lozano et al. 2009 respectively. Reported performance of these methods is also included.