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. 2015 May 7;15:370. doi: 10.1186/s12885-015-1370-2

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© Li et al.; licensee BioMed Central. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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The prognostic significance of lymphovascular invasion in patients stratified by the TNM stage (log-rank test). Stage-match survival analysis showed that the presence of LVI was a prognostic factor for DSS in GC patients with stage I, stage II, stage III or stage IV (A-D). Stage-match survival analysis demonstrated that LVI was a statistically significant predictor for DFS in stage I or stage III and a tendency towards statistical significance was found in stage II (P = 0.086) or stage IV (P = 0.067, E-H).