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. 2015 May 10;15:385. doi: 10.1186/s12885-015-1402-y

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© Castillo-González et al.; licensee BioMed Central. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Kaplan-Meier estimated overall (OS) and disease-free survival (DFS) rates according to ChE activity values. Tumours (n = 57) were split into those that exhibited higher or lower values than the 50^th percentile for AChE activity (1.801 mU/mg protein; a, c), for BChE activity (2.967 mU/mg tissue; b, d) or for the combination of AChE and BChE for OS (e) and DFS (f). Low tumour AChE activity was found to be statistically associated with adverse OS rate (p = 0.014) (a), but not with shorter DFS rate (p = 0.560) (c). High BChE activity in tumours was associated with both adverse OS (p = 0.020, b) and DFS (p = 0.030; d). The combination of AChE and BChE (“AChE high/BChE low” vs “AChE low/BChE high”) were statistically linked with adverse OS (p = 0.002) (e) and DFS (p = 0.047) (f)