Table 1.
Summary of demographic characteristics of HNCSS patients and acetyl- and butyrylcholinesterase activity in upper respiratory epithelium
| AChE activity (mU/mg protein) | BChE activity (mU/mg protein) | ||||||
|---|---|---|---|---|---|---|---|
| Samples | N | ANCT | Tumour | P-value | ANCT | Tumour | P-value |
| Total | 57 | 5.416 ± 0.501 | 3.584 ± 0.633 | 0.002 | 6.350 ± 0.599 | 3.965 ± 0.423 | <0.001 |
| Gender | |||||||
| Male | 53 | 5.094 ± 0.473 | 3.525 ± 0.674 | 0.003 | 6.278 ± 0.638 | 3.952 ± 0.450 | 0.001 |
| Female | 4 | 9.680 ± 2.962 | 4.363 ± 1.395 | 0.273 | 5.730 ± 1.303 | 3.142 ± 0.843 | 0.068 |
| Age | |||||||
| <60 | 18 | 6.175 ± 0.929 | 4.553 ± 1.390 | 0.145 | 7.007 ± 1.311 | 4.572 ± 0.808 | 0.093 |
| >60 | 39 | 5.066 ± 0.593 | 3.136 ± 0.669 | 0.005 | 5.891 ± 0.648 | 3.825 ± 0.495 | 0.002 |
| Tobacco | |||||||
| Non-smoker | 5 | 4.978 ± 1.556 | 3.135 ± 1.820 | 0.225 | 3.891 ± 0.876 | 3.657 ± 0.922 | 0.893 |
| Smoker | 46 | 5.145 ± 0.510 | 3.721 ± 0.741 | 0.017 | 6.852 ± 0.716 | 3.872 ± 0.431 | <0.001 |
| Alcohol | |||||||
| No | 17 | 5.219 ± 0.621 | 3.524 ± 0.695 | 0.290 | 5.807 ± 1.034 | 4.701 ± 0.645 | 0.650 |
| Yes | 16 | 5.921 ± 0.822 | 3.737 ± 1.425 | 0.034 | 6.491 ± 0.745 | 3.746 ± 0.445 | <0.001 |
| Location | |||||||
| Glottic | 29 | 4.736 ± 0.663 | 3.467 ± 0.902 | 0.003 | 5.978 ± 0.794 | 3.612 ± 0.697 | 0.004 |
| Supraglottic | 21 | 5.200 ± 0.607 | 4.423 ± 1.201 | 0.017 | 7.593 ± 1.205 | 4.299 ± 0.603 | 0.007 |
| Other | 7 | 8.374 ± 1.699 | 2.699 ± 0.692 | 0.052 | 4.544 ± 0.530 | 4.362 ± 0.843 | 1.000 |
| Differentiation | |||||||
| Well | 17 | 5.279 ± 0.828 | 4.057 ± 1.473 | 0.227 | 5.013 ± 0.806 | 3.771 ± 0.828 | 0.193 |
| Moderate/Poor | 32 | 5.123 ± 0.637 | 3.631 ± 0.807 | 0.030 | 7.684 ± 0.947 | 4.334 ± 0.622 | 0.002 |
| Clinical Stage | |||||||
| Stage I + II | 19 | 4.660 ± 0.717 | 2.638 ± 0.714 | 0.059 | 6.118 ± 0.849 | 4.046 ± 0.858 | 0.058 |
| Stage III + IV | 36 | 5.319 ± 0.598 | 4.167 ± 0.921 | 0.033 | 6.568 ± 0.829 | 3.951 ± 0.504 | 0.002 |
| Nodal Status | |||||||
| N0 | 30 | 4.780 ± 0.530 | 3.231 ± 0.754 | 0.077 | 6.438 ± 0.857 | 3.624 ± 0.534 | 0.003 |
| N+ | 19 | 5.301 ± 0.943 | 3.432 ± 1.335 | 0.032 | 6.644 ± 1.006 | 4.878 ± 0.838 | 0.039 |
| T Stage | |||||||
| T1 | 4 | 4.707 ± 1.638 | 1.405 ± 0.670 | 0.068 | 4.456 ± 0.583 | 2.228 ± 0.367 | 0.068 |
| T2 | 16 | 4.485 ± 0.790 | 2.893 ± 0.822 | 0.179 | 7.293 ± 1.302 | 4.265 ± 0.952 | 0.063 |
| T3 | 24 | 5.727 ± 1.178 | 4.600 ± 1.562 | 0.382 | 6.522 ± 1.681 | 3.815 ± 0.559 | 0.110 |
| T4 | 11 | 5.224 ± 0.692 | 4.019 ± 1.214 | 0.031 | 6.085 ± 0.853 | 4.331 ± 0.756 | 0.028 |