. Author manuscript; available in PMC: 2015 May 18.

Published in final edited form as: Rev Med Virol. 2009 May;19(3):147–164. doi: 10.1002/rmv.611

Table 1. HCMV pUL37x1\vMIA functional interactions^*.

Interacting Protein	Sub-cellular Location	Activity	References
Adenine nucleotide translocase (ANT)	Inner mitochondrial membrane	anti-apoptosis	Goldmacher et al., 1999 Vieira et al., 2001 Poncet et al., 2006
Bcl-2 family members
BAX	Outer mitochondrial Membrane (OMM)	anti-apoptosis	Poncet et al., 2004; 2006 Arnoult et al., 2004 Pauleau et al., 2007 Norris and Youle, 2008
BAK	OMM	anti-apoptosis	Karbowski et al., 2006 Norris and Youle, 2008
Growth arrest and DNA damage 45 (GADD45)	Cytosol	anti-apoptosis	Smith and Mocarski 2005
Inorganic phosphate carrier (PiC)	Inner mitochondrial membrane	decrease ATP synthesis	Poncet et al., 2006
PiC	Inner mitochondrial membrane	mitochondrial fragmentation	Pauleau et al., 2008
Unknown	ER membrane	Ca²⁺ release from ER	Sharon-Friling et al., 2006
Unknown	Intramitochondrial	inhibition of HtrA2/Omi-dependent, cmvPCD^†	McCormick et al., 2008

Proteins that have been documented to interact with pUL37x1\vMIA are listed. Also included are the probable site of interaction, the resulting activity and the reference for each interacting protein.

^†

Serine protease-dependent CMV infected cell specific programmed cell death

Table 1. HCMV pUL37x1\vMIA functional interactions*.

Table 1. HCMV pUL37x1\vMIA functional interactions^*.