Expression of PKCε in prostate cancer. (a) In silico PKCε mRNA expression profiling in 81 normal/normal adjacent prostate tumors, 48 primary prostate carcinomas and 25 prostate cancer metastasis obtained from a publicly available dataset (GSE6919). PRKCE, PKCε gene. (b) Meta-analysis of PRKCE mRNA expression across 16 prostate microarray studies from the Oncomine database. This meta-analysis shows non-statistically significant differences in PRKCE mRNA expression (combined p-value=0.41) between normal and prostate cancer groups. Red intensity is a representative of the statistical significance in mean difference between normal and protate cancer for each study. (c) Expression of PKCε in “normal” immortalized prostate epithelial RWPE-1 cells vs. prostate cancer cells. This figure was originally published by Garg R, Blando J, Perez CJ, Wang H, Benavides FJ, and Kazanietz MG. in J Biol Chem. 2012 287:37570–37582, © The American Society for Biochemistry and Molecular Biology.