Figure 5.
Phenotype of prostate-specific PKCε transgenic mice. Prostate-specific overexpression of PKCε in mice under the control of the probasin (PB) promoter leads to a preneoplastic phenotype. Representative photomicrographs for H&E, phospho-Akt, phospho-NF-κB and phospho-Stat3 staining in ventral prostates from 12-month old male PB-PKCε mice are shown.