Table 2.

Twelve molecular transcripts that emerged from the microarray analysis

Gene name	GenBank #	Region X group	S1 cortex
WIF1	NM_007191.1	p = 0.003	Ns*
PP1R7	BF718769	p = 0.02	Ns*
FLJ10955	NM_018282.1	p = 0.03	Ns*
PRO0518	AF090934.1	p = 0.006	p = 0.009
DDX21	NM_004728.1	p = 0.009	p = 0.02
SNW1	NM_012245.1	p = 0.01	p = 0.004
NFYB	AI804118	p = 0.02	p = 0.02
HSPC069	AI761110	p = 0.02	p = 0.01
BIRC2	NM_001166.2	p = 0.03	p = 0.01
FBRNP	AA528233	p = 0.03	p = 0.001
PTPRK	NM_002844.1	p = 0.04	p = 0.01
PLOD2	NM_000935.1	p = 0.04	p = 0.003

mRNA levels of 12 molecules conformed to the fMRI spatial profile of Huntington's disease (columns 1-3). A secondary analysis identified three molecules whose expression deficit was restricted to the posterior caudate (column 4, Ns). These hits are considered to best-tracked fMRI-phenotype.

Group represents healthy vs. control. Region x group is the interaction term, including region (anterior vs. posterior caudate) and group.

^*Ns= Not Significant