Liver Dynamic Contrast-Enhanced CT Requirements for Assessment of Hepatocellular Carcinoma.

Characteristic	Specification	Comment
CT imaging equipment	Multidetector CT scanner with ≥ 4 detectors
Contrast agents	Contrast agents at a concentration of ≥ 300 mgI/mL	Necessary to rapidly inject contrast agent at a dose of 520-600 mgI/kg at 2-5 mL/sec
Dynamic phases and timing required for dynamic contrast-enhanced CT	1. Late arterial phase	1. 15-20 sec after maximum aortic enhancement
	2. Portal venous phase	2. 60-80 sec after contrast injection
	3. Delayed phase	3. 2-3 min after contrast injection (optimal timing is 3 min)
Slice thickness/reconstruction interval	Thickness: 5 mm
	Interval: 50-100% of thickness

CT = computed tomography