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Rgg3 antagonists prevent biofilm formation. S. pyogenes wild-type strain NZ131 cultures, grown in 24-well plates, were treated with 10 nM SHP2-C8 and various concentrations of CsA and valspodar. At 20 h, biofilms were assessed by a standard crystal violet staining method. Error bars indicate standard errors from a minimum of three independent experiments.
