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. 2015 May 14;10:66. doi: 10.1186/s13018-015-0209-5

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© Geraghty et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — CVOCA maintains hyaline cartilage structure and ECM contents. Histological stains of a representative cross section of the CVOCA show that hyaline cartilage architecture (superficial, transitional, radial zones) and ECM contents (aggrecan, type II collagen) are maintained in the CVOCA. Stains from left to right: Hematoxylin & Eosin, Safranin O, Type II Collagen, and Type I Collagen. The black arrow points to the tidemark, marking the intersection of the hyaline cartilage and the thin layer of subchondral bone. The scale bar represents 500 μm