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. 2015 May 15;12:94. doi: 10.1186/s12974-015-0311-y

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© Khan et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Effect of ATK on CEC-induced increased levels of PGE2 and LTB4. The levels of PGE2 (A, B) and LTB4 (C, D) were measured using ELISA at 24 h after CEC in the spinal cord tissue from epicenter region (E) and serum. The levels of both PGE2 and LTB4 were significantly increased in CEC + VEH group in the spinal cord (A, C) as well as in the serum (B, D). ATK treatment decreased the levels of both. Data are expressed as mean ± SD (n = 5). Results are presented as pg/mg protein for spinal cord tissue and pg/ml in serum. **p < 0.01, ***p < 0.001 vs. Sham and CEC + ATK, ###p < 0.001 vs. Sham.