Fig 2. Corticosterone serum levels for the counterclockwise (CCW) and clockwise (CW) jet lag protocols.
Serum levels were determined at baseline, after 1 shift, 6 shifts, 5 days recovery and 14 days recovery. Data are presented as mean ± SD. For the first shift, the light dark schedule before the shift is depicted in grey. At baseline a significant 12-hr rhythm was detected, due to the major peak at ZT12 and another peak at ZT0. CircWave peak phases were indicated with (★). Note: as circadian rhythmicity of serum corticosterone levels was lost after 6 shifts, peak phases at the 6th shift are just indicative of the best cosine fit.