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. 2015 Apr 15;16:25. doi: 10.1186/s12881-015-0168-z

Table 4.

Meta-analysis results of special phenotypes

Gene symbol Comparison No. Q Q-P I 2 Model 95% CI P
GSTM1 postive/null 16 60.49 <0.00001 0.75 Random 0.70[0.53,0.92] 0.01
GSTT1 postive/null 15 69.88 <0.00001 0.8 Random 0.69[0.60,0.97] 0.03
G4C14-to-A4T14 P73 GG/GA + AA 2 0.61 0.44 0 Fixed 0.74[0.55,1.00] 0.05
P53 codon 72 C/G 44 268 <0.00001 0.84 Random 1.14[0.99,1.34] 0.07
P53 codon 72 CC/CG + GG 44 242.19 <0.00001 0.83 Random 1.18[0.96,1.42] 0.11
XRCC3 Codon 241 CC/CT + TT 5 6.35 0.17 0.37 Fixed 0.82[0.63,1.06] 0.14
G4C14-to-A4T14 P73 G/A 2 0.1 0.76 0 Fixed 0.83[0.65,1.07] 0.16
GSTP1 AA/AG + GG 2 0.97 0.61 0 Fixed 0.88[0.69,1.11] 0.28
XRCC1 Codon 194 CC/CT + TT 9 17.78 0.02 0.55 Fixed 0.92[0.79,1.08] 0.32
XRCC1 Codon399 GG/GA + AA 12 61.12 <0.0001 0.82 Random 1.18[0.84,1.64] 0.33
XRCC1 Codon399 G/A 12 203.12 <0.00001 0.95 Random 1.23[0.80,1.91] 0.34
XRCC1 Codon194 CC + CT/TT 9 21.11 0.007 0.62 Random 0.78[0.41,1.46] 0.44
GSTP1 A/G 2 0.03 0.86 0 Fixed 0.93[0.76,1.14] 0.48
G4C14-to-A4T14 P73 GG + GA/AA 2 0.89 0.34 0 Fixed 1.23[0.60,2.52] 0.56
P53 codon 72 CC + CG/GG 44 99.69 <0.0001 0.59 Random 1.06[0.90,1.23] 0.57
XRCC1 Codon399 GG + GA/AA 11 171.77 <0.0001 0.94 Random 1.22[0.49,3.01] 0.67
GSTP1 AA + AG/GG 2 0.1 0.76 0 Fixed 0.93[0.51,1.69] 0.80
XRCC3 Codon241 CC + CT/TT 5 13.95 0.003 0.78 Random 0.88[0.27,2.85] 0.83
XRCC1 Codon194 C/T 9 25.69 <0.00001 0.69 Random 0.99[0.73,1.33] 0.93

No, number of studies; OR, combined odds ratio; CI, confidence interval; P, P value.