Table 2. 10 drugs which target genes in MAPK pathway.
Drug ID | Drug name | Drug Target(s) | No. Cell lines screened |
---|---|---|---|
29 | AZ628 | BRAF | 293 |
64 | CMK | RSK | 289 |
166 | FTI-277 | Farnesyl-transferase (FNTA) | 319 |
204 | Tipifarnib | Farnesyl-transferase (FNTA) | 338 |
1014 | RDEA119 | MEK1/2 | 469 |
1015 | CI-1040 | MEK1/2 | 431 |
1036 | PLX4720 | BRAF | 448 |
1060 | PD-0325901 | MEK1/2 | 469 |
1061 | SB590885 | BRAF | 455 |
1062 | AZD6244 | MEK1/2 | 445 |