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. 2015 May 18;10(5):e0127380. doi: 10.1371/journal.pone.0127380

Table 2. 10 drugs which target genes in MAPK pathway.

Drug ID Drug name Drug Target(s) No. Cell lines screened
29 AZ628 BRAF 293
64 CMK RSK 289
166 FTI-277 Farnesyl-transferase (FNTA) 319
204 Tipifarnib Farnesyl-transferase (FNTA) 338
1014 RDEA119 MEK1/2 469
1015 CI-1040 MEK1/2 431
1036 PLX4720 BRAF 448
1060 PD-0325901 MEK1/2 469
1061 SB590885 BRAF 455
1062 AZD6244 MEK1/2 445