Fig 3. LC migration from the epidermis is reduced the in K14E7 mice.

C57Bl/6 and K14E7 mice were painted with FITC on a 15mm² area of abdomen and inguinal lymph nodes harvested 48 h later. Single cell suspensions were stained with CD11c, MHC class II and CD207 (A). The absolute number of FITC positive cells was determined (B). The total migrated LC in the lymph nodes as a percentage of the mean total number of LC in the painted skin is shown (C). *P < 0.05 (Mann-Whitney U test).