Fig 5. Increased expression of costimulatory molecules by E7 occurs in the absence of functional lymphocytes.

Epidermal cell suspensions prepared from RagKO and K14.RagKO mice were stained with antibodies to CD45.2, CD11c, CD207 to identify LC and CD40, CD80 and CD86 to determine their levels of expression. Expression of CD40, CD80 and CD86 (dark line) and isotype staining (light blue line) on LC is shown for representative flow cytometry data (A) and graphically for all data (B). **P < 0.01 (Mann-Whitney U test).