Table 3.
Genotype distribution of IL-6 (− 174G/C) in tobacco chewing, smoking and alcohol consumption.
| OSCC patients | Controls | OR (95% CI) | p-Value | |
|---|---|---|---|---|
| Tobacco chewing | ||||
| Genotypes | n = 167 (%) | n = 88 (%) | ||
| GG | 87 (52.10) | 58 (65.91) | – | |
| GC | 67 (40.12) | 25 (28.41) | 0.560 (0.318–0.987) | 0.051 |
| CC | 13 (7.78) | 5 (5.68) | 0.578 (0.195–1.705) | 0.455 |
| Smoking | ||||
| Genotypes | n = 83 (%) | n = 40 (%) | ||
| GG | 47 (56.63) | 30 (75.00) | – | |
| GC | 31 (37.34) | 7 (17.5) | 0.354 (0.138–0.905) | 0.045⁎ |
| CC | 5 (6.03) | 3 (7.50) | 0.940 (0.209–4.23) | 0.936 |
| Alcohol consumption | ||||
| Genotypes | n = 38 (%) | n = 21 (%) | ||
| GG | 19 (50.00) | 16 (76.19) | – | |
| GC | 15 (39.47) | 3 (14.29) | 0.238 (0.058–0.970) | 0.074 |
| CC | 4 (10.53) | 2 (9.52) | 0.594 (0.096–3.677) | 0.905 |
⁎
Significant value.