Table 1.
Grading of the inflammatory activity in chronic hepatitis according to Ishak et al (the maximum possible scoring is 18)
| Score | |
| Portal inflammation | |
| None | 0 |
| Mild, some or all portal areas | 1 |
| Moderate, some or all portal areas | 2 |
| Moderate/severe, all portal areas | 3 |
| Severe, all portal areas | 4 |
| Periportal or periseptal interface hepatitis (“piecemeal necrosis”) | |
| Absent | 0 |
| Mild (focal, few portal areas) | 1 |
| Mild/moderate (focal, most portal areas) | 2 |
| Moderate (continuous around < 50% of tracts or septa) | 3 |
| Severe (continuous around > 50% of tracts or septa) | 4 |
| Focal parenchymal necrosis | |
| Absent | 0 |
| 1 focus or less per visual field of 100 × magnification | 1 |
| 2-4 foci per 100 × magnification | 2 |
| 5-10 foci per 100 × magnification | 3 |
| More than 10 foci per 100 × magnification | 4 |
| Confluent necrosis | |
| Absent | 0 |
| Focal confluent necrosis | 1 |
| Zone 3 necrosis in some areas | 2 |
| Zone 3 necrosis in most areas | 3 |
| Zone 3 necrosis and occasional portal-central bridging | 4 |
| Zone 3 necrosis and multiple portal-central bridging | 5 |
| Panacinar or multiacinar necrosis | 6 |