Table 2.
Comparison of variables between cases and controls, stratified by BMI
| Variable |
BMI <30 |
P1 |
BMI ≥30 |
P1 | ||||||
|
Cases n = 72 |
Controls n = 153 |
Cases n = 25 |
Controls n = 37 |
|||||||
| No | % | No | % | No | % | No | % | |||
| Gender (male) | 42 | 58.3 | 89 | 58.2 | 1.0 | 13 | 52.0 | 22 | 59.5 | 0.61 |
| Age >50 yr | 38 | 52.8 | 69 | 45.1 | 0.32 | 13 | 52.0 | 21 | 56.8 | 0.80 |
| Leptin ≥9.78 ng/mL | 37 | 51.4 | 61 | 39.9 | 0.11 | 16 | 64.0 | 30 | 81.1 | 0.15 |
| Leptin | 0.042 | 0.252 | ||||||||
| Tercile1<7.67 ng/mL | 22 | 30.6 | 64 | 41.8 | 5 | 20.0 | 4 | 10.8 | ||
| Tercile27.62.4 ng/mL | 25 | 34.7 | 54 | 35 | 3 7 | 28.0 | 9 | 24.3 | ||
| Tercile3>12.4 ng/mL | 25 | 34.7 | 35 | 22.9 | 13 | 52.0 | 24 | 64.9 | ||
| Insulin≥20μU/mL | 9 | 12.5 | 0 | 0 | <0.0001 | 4 | 16.0 | 12 | 32.4 | 0.24 |
| HOMA-IR (>2.5) | 29 | 40.3 | 42 | 27.5 | 0.07 | 15 | 60 | 24 | 64.9 | 0.79 |
| T-chol≥6.21 mmol/L | 19 | 26.4 | 45 | 29.4 | 0.75 | 6 | 24.0 | 6 | 16.2 | 0.52 |
| LDL≥4.14 mmol/L3 | 19 | 27.1 | 40 | 26.7 | 1.0 | 5 | 21.7 | 7 | 18.9 | 1 |
| HDL<1.03 mmol/L | 27 | 37.5 | 50 | 32.7 | 0.55 | 8 | 32.0 | 13 | 35.1 | 1 |
| NHDL ≥4.91 mmol/L | 20 | 27.8 | 43 | 28.1 | 1.0 | 5 | 20.0 | 7 | 18.9 | 1 |
| TGC ≥1.70 mmol/L | 32 | 44.4 | 62 | 40.5 | 0.66 | 17 | 68.0 | 14 | 37.8 | 0.04 |
1F exact test.
2
χ2 for linear trend. 3Five missing values for cases and 2 for controls. BMI, body mass index; T-chol, total cholesterol; LDL, low-density cholesterol; HDL, high density cholesterol; NHDL, non-HDL cholesterol; TGC, triglycerides